GP1BB CLIA Kit for Human(Homo sapiens) | EIAab.comGP1BB CLIA Kit for Human(Homo sapiens)

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GP1BB (Gene name),

Platelet glycoprotein Ib beta chain (Protein name ), GP1BB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GP1BB;

Protein name:

Platelet glycoprotein Ib beta chain(GP-Ib beta;GPIb-beta;GPIbB);

Alternative:

Antigen CD42b-beta;

CD:

CD42c;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

GP-Ib alpha and beta are disulfide linked. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage.

Function:

Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

206

Sequence:

50:

100:

150:

200:

206:

AGTDES

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:2812

MIM:

138720

UniGene:

Hs.283743

STRING:

9606.ENSP00000383382

SMR:

P13224

Pfam:

PF01463

String:

P13224

Uniprot:

P13224

FOR

ELISA Kit for Human GP-Ib beta

Cat.:

E9031h

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Packing:

96T

ELISA Kit for Human GP-Ib beta

Cat.:

E9031m

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96T

ELISA Kit for Human GP-Ib beta

Cat.:

E9031r

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96T

CLIA Kit for Human GP-Ib beta

Cat.:

U9031m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human GP-Ib beta

Cat.:

U9031r

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MSDS:

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Packing:

96T

CLIA Kit for Human GP-Ib beta

Cat.:

U9031h

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Packing:

96T

Polyclonal Antibody for Human GP-Ib beta

Cat.:

P9031Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human GP-Ib beta

Cat.:

P9031Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human GP-Ib beta

Cat.:

P9031Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human GP-Ib beta

Protein for Human GP-Ib beta

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence."
Lopez J.A. , Chung D.W. , Fujikawa K. , Hagen F.S. , Davie E.W. , Roth G.J.
Proc. Natl. Acad. Sci. U.S.A.85:2135-2139(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);GLYCOSYLATION AT ASN-66
2.

"Structural characterization and chromosomal location of the gene encoding human platelet glycoprotein Ib beta."
Yagi M. , Edelhoff S. , Disteche C.M. , Roth G.J.
J. Biol. Chem.269:17424-17427(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Brain.
3.

"Complementary DNA cloning of the alternatively expressed endothelial cell glycoprotein Ib beta (GPIb beta) and localization of the GPIb beta gene to chromosome 22."
Kelly M.D. , Essex D.W. , Shapiro S.S. , Meloni F.J. , Druck T. , Huebner K. , Konkle B.A.
J. Clin. Invest.93:2417-2424(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
tissue: Umbilical vein.
4.

"Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence."
Zieger B. , Hashimoto Y. , Ware J.
J. Clin. Invest.99:520-525(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.

"Missense mutations of the glycoprotein (GP) Ib beta gene impairing the GPIb alpha/beta disulfide linkage in a family with giant platelet disorder."
Kunishima S. , Lopez J.A. , Kobayashi S. , Imai N. , Kamiya T. , Saito H. , Naoe T.
Blood89:2404-2412(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 11-206;VARIANTS BSS CYS-113 AND PRO-133
6.

"Isolation and characterization of the alpha and beta chains of human platelet glycoprotein Ib."
Canfield V.A. , Ozols J. , Nugent D. , Roth G.J.
Biochem. Biophys. Res. Commun.147:526-534(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-40
7.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 83-92 AND 190-200
tissue: Platelet.
8.

"Platelet glycoprotein Ib beta is phosphorylated on serine 166 by cyclic AMP-dependent protein kinase."
Wardell M.R. , Reynolds C.C. , Berndt M.C. , Wallace R.W. , Fox J.E.B.
J. Biol. Chem.264:15656-15661(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-191;PROTEIN SEQUENCE OF 186-200
9.

"Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet."
Luo S.Z. , Mo X. , Afshar-Kharghan V. , Srinivasan S. , Lopez J.A. , Li R.
Blood109:603-609(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;INTERCHAIN DISULFIDE BOND
10.

"Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
Carrascal M. , Ovelleiro D. , Casas V. , Gay M. , Abian J.
J. Proteome Res.7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: T-cell.
11.

"Phosphoproteome of resting human platelets."
Zahedi R.P. , Lewandrowski U. , Wiesner J. , Wortelkamp S. , Moebius J. , Schuetz C. , Walter U. , Gambaryan S. , Sickmann A.
J. Proteome Res.7:526-534(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-191 AND THR-193;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Platelet.
12.

"Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbbeta and a GPIbbeta/GPIX chimera."
McEwan P.A. , Yang W. , Carr K.H. , Mo X. , Zheng X. , Li R. , Emsley J.
Blood118:5292-5301(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.24 ANGSTROMS) OF 26-146;GLYCOSYLATION AT ASN-66;DISULFIDE BONDS

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